Abstract

Summary

This paper reviews the impact of genetically or environmentally induced molecular clock disruption and the interplay between the circadian system and metabolic processes, discussing mechanisms responsible for diet-induced circadian desynchrony and the impact of nutritional cues in inter-organ communication.
Categories

Categories

Obesity and Weight Management: The paper discusses how disruption of circadian rhythms contributes to the development of obesity and metabolic disease, and how inappropriate timing of food intake can lead to disruptions of the temporal coordination of metabolism.
Cognitive function and memory: The paper discusses the role of the circadian clock in coordinating anabolic and catabolic processes in peripheral tissues with the behavioral sleep–wake and fasting–feeding cycles, which can impact cognitive function.
Sleep and insomnia: The paper discusses how disruptions in circadian rhythms can impact sleep patterns, contributing to conditions such as insomnia.
Shift work: The paper discusses how humans under circadian misalignment, such as shift work or jet lag, can experience disruption of circadian rhythms, contributing to the development of obesity and metabolic disease.
Jet lag: The paper discusses how jet lag can cause disruption of circadian rhythms, contributing to the development of obesity and metabolic disease.
Hormone regulation: The paper discusses the role of the circadian clock in hormone regulation, particularly in relation to the sleep–wake and fasting–feeding cycles.
Authors

Author(s)

E Maury
Publication Date

Publication Year

2019
Citations

Number of Citations

126
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