Abstract

Summary

This paper reviews the molecular regulations of circadian rhythm and its implications for physiology and diseases, discussing the role of the biological clock in controlling physiological functions of almost all tissues and organs, and its implications in human pathologies such as cancer and inflammatory diseases.
Categories

Categories

Cancer treatment and prevention: The paper discusses how disruption of circadian rhythm can affect physiological processes relevant to human diseases, including cancer, and how understanding this field can contribute to the establishment of a circadian precision medicine.
Immune system function and health: The paper discusses how the biological clock plays a key role in controlling physiological functions of almost all tissues and organs, including the immune response.
Hormone regulation: The paper discusses how the circadian clock regulates several intracellular signaling pathways, including hormone regulation.
Phototherapy: The paper discusses how circadian rhythms can be challenged by environmental factors, including light/dark cycles, and how this can have implications for human pathologies.
Lighting Design Considerations: The paper discusses how the daily light–dark cycle represents the primary external synchronizer of circadian rhythms, which is relevant to lighting design considerations.
Authors

Author(s)

F Fagiani, D Di Marino, A Romagnoli
Publication Date

Publication Year

2022
Citations

Number of Citations

96
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