Abstract

Summary

The paper discusses the role of intrinsically photosensitive retinal ganglion cells (ipRGCs) in circadian rhythm and how they may contribute to the prevalence of epileptic activity in sleep and drowsiness states, particularly in Temporal Lobe Epilepsy (TLE).
Categories

Categories

Sleep and insomnia: The paper discusses the prevalence of epileptic activity during sleep and drowsiness states, suggesting that intrinsically photosensitive retinal ganglion cells (ipRGCs) play a role in this phenomenon.
Cognitive function and memory: The paper discusses the role of the hippocampus, a brain region involved in cognitive functions and memory, in the prevalence of epileptic activity during sleep and drowsiness states.
Depression: The paper discusses the high comorbidity of Temporal Lobe Epilepsy (TLE) and depression, suggesting a possible commonality in the mechanisms of both conditions.
Hormone regulation: The paper discusses the role of the suprachiasmatic nucleus (SCN) in regulating the hippocampal circadian variations, which may affect the prevalence of epileptic activity during sleep and drowsiness states.
Authors

Author(s)

E Levichkina, IN Pigarev, DB Grayden, S Petrou
Publication Date

Publication Year

2023
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