Prefrontal cortex neurons encode ambient light intensity differentially across regions and layers
Summary:
The paper investigates the photosensitivity of neurons in the medial prefrontal cortex (mPFC), finding that over half of studied mPFC neurons showed photosensitivity, with potential implications for psychiatric and addiction disorders.
Categories
- Cognitive function and memory: The paper explores how light can affect cognitive processes in the medial prefrontal cortex, including decision-making and working memory.
- Depression: The paper discusses how light-dependent alteration in depression-like behaviours in animals is associated with the transmission of light signals to the mPFC.
- Substance Abuse and Dependence: The paper suggests that prefrontal photosensitivity could be studied as a therapeutic target in addiction disorders.
- Psychiatric Disorders: The paper posits that prefrontal photosensitivity could represent a substrate of light-susceptible, mPFC-mediated functions, which could be studied as a therapeutic target in psychiatric disorders.
Author(s)
S Sabbah, E Zangen, S Hadar, C Lawrence, H Rasras
Publication Year:
2023
Number of Citations:
0
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