Summary
The paper discusses the impact of opioid drugs on sleep/wake dysfunction, focusing on the role of intrinsically photosensitive retinal ganglion cells (ipRGCs) and µ-opioid receptors (MORs) in the eye in mediating sleep/wake rhythms in response to environmental light/dark cycles.
Categories
Sleep and insomnia: The paper investigates how opioid drugs disrupt sleep/wake rhythms, contributing to sleep disorders such as insomnia.
Substance Abuse and Dependence: The research focuses on the effects of chronic opioid use, a form of substance abuse, on sleep/wake dysfunction.
Eye health: The study explores the role of ipRGCs in the eye in transmitting light information to the brain's sleep/wake circuitry, and how this process is disrupted by opioid drugs.
Cognitive function and memory: The paper indirectly relates to cognitive function and memory by discussing how disrupted sleep/wake rhythms, caused by opioid drugs, can impact cognitive processes.
Phototherapy: The research indirectly relates to phototherapy by discussing the role of light in regulating sleep/wake behavior and how this process is disrupted by opioid drugs.
Author(s)
N Bergum
Publication Year
2023
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