Abstract

Summary

This paper discusses the impact of opioids on sleep/wake behavior, focusing on the role of intrinsically photosensitive retinal ganglion cells (ipRGCs) and their μ-opioid receptors (MORs) in modulating sleep/wake cycles, and the potential therapeutic interventions for opioid-induced sleep disturbances.
Categories

Categories

Sleep and insomnia: The paper investigates how opioids, specifically morphine, impact sleep/wake behavior, contributing to sleep disturbances such as insomnia and daytime sleepiness.
Substance Abuse and Dependence: The paper discusses the effects of chronic opioid use, including persistent sleep disturbances and increased drug craving and relapse.
Eye health: The paper explores the role of intrinsically photosensitive retinal ganglion cells (ipRGCs) and their μ-opioid receptors (MORs) in modulating sleep/wake cycles.
Pain management: The paper discusses the analgesic effects of opioids, such as morphine, and their impact on sleep/wake behavior in individuals experiencing chronic pain.
Authors

Author(s)

CT Berezin
Publication Date

Publication Year

2023
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