Abstract

Summary

This paper discusses the role of the circadian gas-responsive hemeprotein NPAS2 in physiology and pathology, including its involvement in regulating circadian rhythms and sleep–wake cycles, metabolism regulation, and its potential contribution to health issues such as sleep disturbances, psychiatric disorders, and diseases.
Categories

Categories

Sleep and insomnia: The paper discusses the role of NPAS2 in regulating sleep–wake cycles and how its dysregulation can lead to sleep disturbances.
Cognitive function and memory: The paper mentions the importance of NPAS2 for the function of the central nervous system in mammals.
Cancer treatment and prevention: The paper discusses the involvement of NPAS2 in carcinogenesis and its potential as a biomarker for prevention strategies and therapeutic approaches.
Heart disease: The paper mentions the role of NPAS2 in cardiovascular function.
Psychiatric Disorders: The paper discusses how dysregulation of NPAS2 may contribute to psychiatric disorders.
Hormone regulation: The paper discusses the role of NPAS2 in the regulation of metabolic pathways, which involves hormone regulation.
Authors

Author(s)

E Murgo, T Colangelo, MM Bellet, F Malatesta
Publication Date

Publication Year

2023
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