Abstract

Summary

This paper investigates the interaction between circadian disruption and prenatal immune activation in relation to neurodevelopmental disorders, using a combination of behavioral, cellular, and molecular approaches.
Categories

Categories

Autism Spectrum Disorder: The paper discusses Autism Spectrum Disorder as a neurodevelopmental disorder that can be influenced by genetic risk variants and environmental risk factors such as prenatal exposure to maternal infection and circadian rhythm disruption.
Sleep and insomnia: The paper discusses the role of circadian rhythm disruption, which can lead to sleep disturbances, as a risk factor for neurodevelopmental disorders.
Cognitive function and memory: The paper discusses how circadian disruption and prenatal immune activation can lead to cognitive deficits in offspring.
Psychiatric Disorders: The paper discusses neurodevelopmental disorders, including schizophrenia, which are considered psychiatric disorders.
Hormone regulation: The paper discusses the role of prenatal immune activation, which involves hormonal changes, in the development of neurodevelopmental disorders.
Lighting Design Considerations: The paper discusses the use of constant light exposure as a method to induce environmental circadian disruption in experimental models.
Well-being: The paper discusses the potential for circadian-based therapies to prevent or mitigate symptoms in neurodevelopmental disorders, which would improve the well-being of affected individuals.
Authors

Author(s)

T Delorme
Publication Date

Publication Year

2023
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